Masthead

Programme

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Sunday 17th June

14.00 – 19.30

Registration Open and Evening Mixer

Monday 18th June

08.00 – 19.30

Registration Open

09.00 – 09.05

Welcome from Bill Hill

09.05 - 10.40

The genetic architecture of quantitative traits
Chair: Bruce Walsh (University of Arizona)

09.05 – 09.20

Introduction: The quantitative genetics landscape in 2012
Bruce Walsh

09.20 – 10.00

O-1 From Galton to GWAS (and beyond): what have we learned about quantitative traits in human populations?
Peter Visscher (University of Queensland, Brisbane)

10.00 - 10.40

O-2 Uniting the world's maize germplasm diversity for trait dissection and accelerated breeding
Ed Buckler (USDA, Ithaca)

10.40 – 11.10

Tea/Coffee

11.10 – 11.40

The genetic architecture of quantitative traits
Chair: Bruce Walsh

O-3 An improved method for heritability estimation provides insights into the genetic architecture of epilepsy
Doug Speed (University College, London)

11.40 – 12.40

Genetics Society Mendel Lecture
Chair: Veronica van Heyningen (President, Genetics Society)

O-4 Secrets of the human genome
Eric Lander (Broad Institute, MIT & Harvard)

12.40 – 13.40

Lunch

13.40 - 15.20

Evolutionary quantitative genetics
Chair: Derek Roff ( University of California Riverside)

13.40 – 14.20

O-5 Evolution of genetic variance under selection
Mark Blows (University of Queensland, Brisbane)

14.20 – 14.40

O-6 Plants in heterogeneous environments: determining when phenotypic plasticity is adaptive
Diane Byers (Illinois State University, Normal)

14.40 – 15.00

O-7 Discovery of cryptic genetic variation in C. elegans embryogenesis
Annalise Paaby (New York University)

15.00 – 15.20

O-8 Genomic comparisons between selected and relaxed chicken lines
Mats Pettersson (Swedish University of Agricultural Sciences, Uppsala)

15.20 – 15.50

Tea/Coffee

15.50 - 17.20

Evolutionary quantitative genetics
Chair: Derek Roff

15.50 – 16.30

O-9 Gene interactions underlying the evolution of complex traits
Patrick Phillips (University Oregon, Eugene)

16.30 – 17.00

O-10 What, me natural? Patterns of selection in wild systems and their theoretical implications
Jarrod Hadfield (University of Edinburgh & Oxford)

17.00 – 17.20

O-11 The deceit of monogamy: Quantitative genetic insights into the evolutionary ecology of polyandry in the wild
Jane Reid (University of Aberdeen)

17.30 – 19.30

Poster Session

Tuesday 19th June

08.00 – 19.30

Registration Open

09.00 - 10.40

Variation in the genome
Chair: Greg Gibson (Georgia Tech, Atlanta)

09.00 – 09.40

O-12 Causes and consequences of new mutations
Matt Hurles (Sanger Institute, Cambridge)

09.40 – 10.00

O-13 The role of genetic variations on gene expression and splicing in multiple regions of control human post-mortem brain tissue
Daniah Trabzuni (University College London & King Faisal Specialist Hospital, Riyadh)

10.00 – 10.20:

O-14 Population genetics revealed by enormous structural variations discovered by population-scale sequencing
Quan Long (Gregor Mendel Institute, Vienna)

10.20 – 10.40

O-15 Variation in transcription factor binding among humans
Maya Kasowski (Stanford University, California)

10.40 – 11.10

Tea/Coffee

11.10 - 12.40

Variation in the genome
Chair: Greg Gibson

11.10 – 11.50

O-16 Mapping the epigenetic basis of complex traits in Arabidopsis
Frank Johannes (University of Groningen)

11.50 – 12.20

O-17 The role of tandem repeats in mRNA and protein expression homeostasis
Sreenivas Chavali (MRC Lab Molecular Biology, Cambridge)

12.20 – 12.40

O-18 Dissecting the contribution of regulatory sequence variation to quantitative haematological traits using maps of open chromatin in primary human blood cells
Cornelis Albers (University of Cambridge & Sanger Institute)

12.40 – 13.40

Lunch/Exhibition/Poster viewing

13.40 - 15.20

Advances from numerical methods
Chair: David Balding (University College, London)

13.40 – 14.20

O-19 Statistical methods for the genetic analysis of arbitrarily structured populations
John Storey (Princeton University)

14.20 – 14.40

O-20 CLIP Test: a new fast and simple method to distinguish between linked or pleiotropic quantitative trait loci in linkage disequilibrium analysis
Jean-Michel Elsen (INRA, Toulouse)

14.40 – 15.00

O-21 Sparse factor models for estimating the genetic architecture of gene expression traits
Daniel Runcie (Duke University, Durham, NC)

15.00 – 15.20

O-22 Big data, small cost – combining low-pass genome sequencing with long-range phasing and haplotype library imputation to create more powerful data for genomic prediction in plants and animals
John Hickey (University of New England, Armidale)

15.20 – 15.50

Tea/Coffee

15.50 - 17.20

Advances from numerical methods
Chair: David Balding

15.50 – 16.30

O-23 Haplotype phasing using next- generation sequencing reads
Jonathan Marchini (Oxford University)

16.30 – 17.00

 

O-24 Whole-genome prediction of human complex traits using data from related and unrelated individuals
Gustavo de los Campos (University of Alabama, Birmingham, AI)

17.00 – 17.20

O-25 Relaxing the genetic model to identify quantitative trait loci having heterogeneous effects
Hugues Aschard ( Harvard University, Cambridge, Massachusetts)

17.20 – 19.30

Poster Session

Wednesday 20th June

08.00 – 18.00

Registration Open

09.00 - 10.40

Technical advances and emerging areas
Chair: Marie-Anne Felix, École Normale Supérieure, Paris

09.00 – 09.40

O-26 Whole genome phasing and diploid variant annotations
Nik Schork (Scripps Institute, UC San Diego)

09.40 – 10.00

O-27 Low depth, whole genome sequencing of Dai population demonstrates superiority over use of whole genome genotyping arrays in uncovering population structure, demographic history, selective pressures and phenotype associations in non-european populations
Lachlan Coin (BGI Shenzhen & Imperial College, London)

10.00 – 10.20

O-28 The relationship between binary disease status and underlying heterogeneity in susceptibility and infectivity
Debby Lipschutz-Powell (Roslin Institute, University of Edinburgh)

10.20 – 10.40

O-29 How do hosts shape their microbial communities?
Matthew Horton (University of Chicago)

10.40 – 11.10

Tea/Coffee

11.10 - 12.40

Technical advances and emerging areas
Chair: Marie-Anne Felix

11.10 – 11.50

O-30 Quantitative association genetics of high dimensional cellular traits: extending beyond expression QTLs
Richard Durbin (Sanger Institute, Cambridge)

11.50 – 12.20

O-31 Systems biology of genetic variation in Drosophila: InR/TOR
Sergey Nuzhdin (University of California, Davis)

12.20 – 12.40

O-32 Whole genome sequence analysis of a large Scottish family with bipolar disorder
Kathryn Evans (University of Edinburgh)

Wednesday PM

Genetics society postgraduate symposium

Free for arranging associated symposia

Thursday 21st June

08.00 – 17.30

Registration Open

09.00 - 10.40

Bridging the genotype-phenotype gap
Chair: Michel Georges (University of Liege)

09.00 – 09.40

O-33 Bridging the genotype-phenotype gap: lessons from Drosophila
Trudy Mackay (North Carolina State University, Raleigh)

09.40 – 10.00

O-34 Heterosis as a systemic property emerging from the non-linearity of the genotype-phenotype relationship: evidence from metabolic models and test-tube genetics
Dominique de Vienne (University Paris XI, Gif-sur-Yvette)

10.00 – 10.20

O-35 Discovering early and late regulators of haematopoiesis through large-scale genomic analyses
Nicole Soranzo (Sanger Institute, Cambridge)

10.20 – 10.40

O-36 A sexual ornament in chickens is determined by pleiotropic alleles at HAO1 and BMP2, selected during domestication
Dominic Wright (Linköping University, Sweden)

10.40 – 11.10

Tea/Coffee

11.10 - 12.40

Bridging the genotype-phenotype gap
Chair: Michel Georges

11.10 – 11.50

O-37 Diamonds in the dirt: biological and translational insights into type 2 diabetes from large-scale genetic studies
Mark McCarthy (University of Oxford)

11.50 – 12.20

O-38 The biologic relevance of eQTLs: a genome wide confirmation of eQTLs using two types of inbred populations in C. Elegans
Mark Sterken (Wageningen University)

12.20 – 12.40

O-39 Quantitative genetics of Drosophila life span
Michael Magwire (North Carolina State University, Raleigh)

12.40 - 13.40

Lunch/Exhibition/Poster viewing

13.40 - 15.20

The genetic architecture of quantitative traits 2
Chair: Bruce Weir (University of Washington, Seattle)

13.40 – 14.20

The Genetics Society Balfour Lecture
O-40 Variance controlling genes and their role in the genetic architecture of complex traits
Orjan Carlborg (Swedish University of Agricultural Sciences, Uppsala)

14.20 – 14.40

O-41 GWAS: 2D, or not 2D: that is the question
Gibran Hemani (Roslin Institute, University of Edinburgh & University of Queensland, Brisbane)

14.40 – 15.00

O-42 Knowledge-driven analysis identified a gene-gene interaction affecting high-density lipoprotein cholesterol levels in multi-ethnic populations
Alon Keinan (Cornell University, NY)

15.00 – 15.20

O-43The genetic architecture of quantitative traits: lessons from biochemical markers for disease
Beben Benyamin (University of Queensland, Brisbane)  

15.20 – 15.50

Tea/Coffee

15.50 - 17.20

The genetic architecture of quantitative traits  2
Chair: Bruce Weir

15.50 – 16.30:

O-44 From Castle to the Collaborative Cross: evolution of the mouse in quantitative genetics research
Daniel Pomp (University of North Carolina, Chapel Hill)

16.30 – 17.00

O-45 Genetic architecture and evolution of quantitative traits
Mike Goddard (University of Melbourne)

17.00 – 17.20

O-46 The quantitative genetics of phenotypic robustness
Hunter Fraser (Stanford University)

Friday 22nd June

08.00 – 17.30

Registration Open

09.00 - 10.40

Interactions among individuals and with the environment
Chair: Albrecht Melchinger (University of Hohenheim)

09.00 – 09.40

O-47 Studying the genotype-phenotype map in Arabidopsis
Magnus Nordborg (Gregor Mendel Institute, Vienna)

09.40 – 10.00

O-48 Novel methods of GWAS for mapping genes of complex traits and their applications in crop breeding
Jun Zhu (Zhejiang University)

10.00 – 10.20

O-49 Nonlinear genotype x environment interaction
Rong-Cai Yang (University of Alberta, Edmonton)

10.20 – 10.40

O-50 Applying quantitative genetics to epidemics and disease resistance: implications of dynamic and noisy data
Steve Bishop (Roslin Institute and R(D)SVS, Edinburgh

10.40 – 11.10

Tea/Coffee

11.10 - 12.40

Interactions among individuals and with the environment
Chair: Albrecht Melchinger

11.10 – 11.50

O-51 The consequences of indirect genetic effects for heritable variation and response To selection
Piter Bijma (Wageningen University)

11.50 – 12.20

O-52 The genetics of social dominance: does competition cause constraint?
Alastair Wilson (University of Edinburgh)

12.20 – 12.40

O-53 Simple and effective methods of addressing competitive effects in animal breeding programs
William Muir (Purdue University, Indiana)

12.40 – 13.40

Lunch/Exhibition/Poster viewing

13.40 - 15.20

Genomic information in prediction
Chair: Theo Meuwissen (Norwegian University of Life Science)

13.40 – 14.20

O-54 Towards genomic prediction from genome sequence data and the 1000 bull genomes project
Ben Hayes (Victorian Department of Primary Industries, Melbourne)

14.20 – 14.40

O-55 Using whole genome sequence data to predict quantitative trait phenotypes in Drosophila melanogaster
Ulrike Ober (Georg-August-University Göttingen)

14.40 – 15.00

O-56 Next generation breeding using genotyping-by-sequencing
Jose Crossa (CIMMYT, Mexico)

15.00 – 15.20

O-57 Genomic-BLUP decoded: a look into the black box
David Habier (Iowa State University)

15.20 – 15.50

Tea/Coffee

15.50 - 17.30

Genomic information in prediction
Chair: Theo Meuwissen

15.50 – 16.30

O-58 Predicting disease risk from marker genotypes under a polygenic model
Pak Sham (University of Hong Kong)

16.30 – 17.00

O-59 Genome-based prediction in highly structured plant populations
Chris-Carolin Schoen (Technical University, Munich)

17.00 – 17.20

O-60 Genomic prediction of colorectal cancer risk using GBLUP
Isobel Stewart (MRC Human Genetice & University of Edinburgh)

17.20 – 17.30

Close of Conference - Thanks

Friday EVENING

Banquet at Dynamic Earth


*On Wednesday afternoon a Genetics Society Postgraduate Conference will be held. (Email: Kay Boulton). There will be opportunities for small symposia to be arranged by participants on Wednesday afternoon or at lunchtimes/early evening.

Further details will be provided at a later date.

Posters will be on view in the area used for coffee/tea breaks and lunch and at the designated early evening sessions.

Conference organisers: In Conference Ltd. www.in-conference.org.uk - Site by Source